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Boil water notice for East Olean after water main break

By JIM ECKSTROM jeckstrom@oleantimesherald.com

August 18, 2026

OLEAN — Mayor Amy B. Sherburne advised Tuesday afternoon that East Olean residents boil their water for consumption until further notice after a water...

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Home Online Features TransCode Therapeutics Reports Further Progress on Phase 1a Clinical Trial with No Dose Limiting Toxicities Reported in Patients with Metastatic Cancer

TransCode Therapeutics Reports Further Progress on Phase 1a Clinical Trial with No Dose Limiting Toxicities Reported in Patients with Metastatic Cancer

Press Releases

TransCode Therapeutics, Inc.

May 1, 2025

TransCode Therapeutics Reports Further Progress on Phase 1a Clinical Trial with No Dose Limiting Toxicities Reported in Patients with Metastatic Cancer

A total of 13 patients treated with four escalating doses of TTX-MC138No significant safety or dose limiting toxicities reportedTwo patients have so far maintained stable disease on treatment for at

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Olean Times Herald

Local & Social

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Local News, News

State & Union: Turning back the clock on Olean

September 29, 2026

From a visit from “Carrie Hatchet” and fighting tuberculosis to planning for nuclear war, from readying for swine flu to helping those hurting from 9/...

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Lifestyle, Lifestyles

Dear Abby: Stay-at-home dad feels pressure to work

September 29, 2026

DEAR ABBY: My wife and I have been married for 20 years. She's an academic, and we've lived a transient lifestyle to accommodate her career. She had a...

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Wilczewski takes 4th, A-L girls notch 3rd at Queensbury

Local Sports, Sports

WEEKEND HIGH SCHOOL WRAP

Wilczewski takes 4th, A-L girls notch 3rd at Queensbury

September 28, 2026

QUEENSBURY — The Allegany-Limestone cross country teams traveled nearly six hours to compete in the prestigious, state-wide Queensbury Adirondack XC I...

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Local Sports, Soccer, Sports

German’s hat trick keys Portville; E/F tops Salamanca

September 28, 2026

SOUTH DAYTON — Colin German recorded a hat trick, including a pair of goals two minutes apart midway through the first half to start an eventual scori...

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Irons, Vecchio key A-L swimmers past Chautauqua Lake

Local Sports, Sports

HIGH SCHOOL WRAP

Irons, Vecchio key A-L swimmers past Chautauqua Lake

September 28, 2026

ALLEGANY — Quinn Irons (200 freestyle, 100 back) and Sammi Vecchio (200 IM, 100 butterfly) both won two events and swam on the top 200 medley relay te...

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TransCode Therapeutics Reports Further Progress on Phase 1a Clinical Trial with No Dose Limiting Toxicities Reported in Patients with Metastatic Cancer

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