DEC orders changes at Great Lakes Cheese after Ischua Creek fish kill
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DEC orders changes at Great Lakes Cheese after Ischua Creek fish kill
By BOB CLARK bclark@oleantimesherald.com 
August 29, 2025
FRANKLINVILLE — State environmental officers said immediate changes are needed after a fish kill in Ischua Creek was triggered by pollution from the G...
Home Online Features Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing
Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing
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Spyre Therapeutics, Inc.  
November 12, 2024

Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing

SPY001 was well tolerated with a favorable safety profile consistent with the anti-α4β7 class

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